As we have reviewed previously, our mitochondria are working constantly to produce ATP cell energy to run the body and keep us vibrant and alive. The mitochondria require a constant supply of fuel, in the form of glucose, fat and ketones, to burn for energy production. Our mitochondria also require a generous supply of micronutrients, such as vitamins, minerals and polyphenols, to execute all of the chemical processes required to generate ATP.


With our oxygen-based metabolism, mitochondria produce enormous amounts of oxygen free radicals that can inflict damage to our mitochondria. Just as the kitchen is the most likely place in our homes to get burned, our mitochondria are the parts of our cells most vulnerable to oxidative stress and injury. With aging, chronic inflammation, oxidation, and hormone deficiencies, we experience mitochondrial decay that contributes to fatigue, muscle loss, memory loss, less efficient cardiovascular systems and weight gain. It is crucial that we provide plentiful nutrients, antioxidants and anti-inflammatory reinforcements to help aid our mitochondrial from assault.

Our whole-food, balanced diet, inclusive of quality meats, poultry, seafood, eggs, vegetables, fruit, seeds and nuts; provides macronutrients, micronutrients, minerals, and polyphenols. All key nutrients required by the mitochondria to efficiently produce ATP energy and to offset mitochondrial decay.

Targeted supplements, in conjunction with our nutritious diets, help augment cell energy production to take our results to the next level and to slow the pace of aging.

Remember, the highest quantity of mitochondria occur in brain, heart and skeletal muscles, our high energy requiring organs. Thus, when we support our mitochondrial troops, we upgrade brain, heart, muscle function, and our metabolism dramatically.

Mitochondria have unrelenting exposure to oxidative stress and are working 24/7 to produce energy……….they need our reinforcement!

Key components of our mitochondrial makeover supplement program include:

  • Supporting mitochondrial function by supplying them with necessary nutrients.
  • Protecting mitochondria from incessant oxidative stress.
  • Increasing mitochondrial ATP energy production.
  • Stimulating mitochondrial biogenesis to produce new mitochondria.
  • Decreasing inflammation and oxidative stress to preserve and protect mitochondria and to slow mitochondrial decay.

Of course our nutrition, intermittent fasting, nutritional ketosis, and targeted supplements all work synergistically to cover theses key components of our mitochondrial makeover program.

Some of our targeted supplements contribute specific roles to either protect mitochondria, to improve mitochondrial function and energy production, or to stimulate production of new mitochondria via mitochondrial biogenesis. These supplements work collectively to reach all of our key components simultaneously.

COQ10 (COENZYME Q10): helps mitochondria produce more energy and reduces oxidative stress.

Krill oil/Omega-3 fatty acids: provides Astaxanthin, EPA and DHA to protect mitochondrial membranes from oxidation and dampen inflammation.

L-Carnitine: shuttles fatty acids into the mitochondrial to burn for energy.

PQQ (Pyrroloquinoline quinone): reduces oxidative stress, reduces inflammation, and enhances mitochondrial function as well as promoting mitochondrial biogenesis.

Acetyl –L- Carnitine: bolsters ATP energy production.

Alpha-Lipoic acid: reduces mitochondrial decay and stimulates biogenesis.

Resveratrol/Pterostilbene: improves mitochondrial function and triggers biogenesis.

Nicotinamide Riboside (vitamin B3 variant): is a precursor to NAD+ (Nicotinamide Adenine Dinucleotide), a coenzyme found in all cells and boosts ATP production.

D-Ribose:provides raw materials for ATP production, reinforcing brain, heart and muscle function.

L-Arginine/alpha-ketoglutarate: an amino acid and keto-acid that increases nitric oxide production and confers protective effects on the mitochondria.

Many of the mitochondrial support products available today combine several of these supplements conveniently together for ease of use as well as balanced impact for robust mitochondrial restoration and performance.

Author: frankcomstock

I am a physician with an anti-aging medical practice in Tucson called Lifestyle Spectrum. I am the author of ANTIAGING 101: Course Manual

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